Dax Ryan Locke, born to Julie and Austin Locke on June 26, 2007, was diagnosed with AML M7, a rare form of leukemia, when he was 13 months old. The Heart of Christmas is set in Washington, Illinois and at St. Jude Children's Research Hospital, one of the world's premier centers for the research and treatment of pediatric cancer and other deadly diseases in children. Told in flashback from the perspective of Megan (Candace Cameron Bure), a successful businesswoman, wife and mother of two, the storyline unfolds when her commitment to faith and family is renewed after reading the blog of Julie Locke, (http://www.caringbridge.org/visit/daxlocke), the online journal that Julie kept after Dax was diagnosed with Acute Myeloid Leukemia (AML) (http://theheartofchristmasmovie.com/story.php).